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Download Book Cancer Biology And Treatment in PDF format. You can Read Online Cancer Biology And Treatment here in PDF, EPUB, Mobi or Docx formats.Cell Death Signaling In Cancer Biology And Treatment
Author :Daniel JohnsonISBN :9781461458470
Genre :Science
File Size : 69.21 MB
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A key goal in the treatment of cancer is to achieve selective and efficient killing of tumor cells. The aim of Cell Death Signaling in Cancer Biology and Treatment is to describe state-of-the-art approaches and future opportunities for achieving this goal by targeting mechanisms and pathways that regulate cancer cell death. In this book, molecular defects in cell death signaling that characterize cancer cells, including dysregulation of cell death due to overexpression/hyperactivation of oncoproteins, as well as the loss of tumor suppressor proteins will be described. The potential for targeting microRNAs will be discussed. Multiple chapters will describe preclinical and clinical approaches that are currently being used to target epigenetic modifications, DNA repair pathways, and protein chaperones, as a means of provoking tumor cell death. Finally, the development and application of novel agents and approaches for targeting specific components of cell death signaling pathways and machinery will be reviewed.
Principles Of Cancer Biology
Author :Lewis J. KleinsmithISBN :UOM:39015063094331
Genre :Health & Fitness
File Size : 23.50 MB
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Principles of Cancer Biology,is an engaging book focused on providing readers with a “big picture” view of cancer. Author Lewis Kleinsmith has written an instructional text focusing on key concepts for a general audience. Each chapter contains a list of suggested readings that expand the detail as needed. The text also emphasizes the scientific evidence that underlies cancer biology, and teaches readers to think critically about this evidence- as there are constantly new “breakthroughs” and reports in this field. For readers who need the review, there are brief reviews of several topics related to DNA replication and repair, cell division, cell signaling, and inheritance patterns in chapters where these subjects are relevant. By including these reviews, the text is both accessible and engaging to a broad audience of readers who are studying cancer biology for the first time, as well as an interested general audience.What Is Cancer, Profile of a Cancer Cell, How Cancers Spread, Identifying the Causes of Cancer, Chemicals and Cancer, Radiation and Cancer, Infectious Agents and Cancer, Heredity and Cancer, Oncogenes, Tumor Suppressor Genes and Cancer Overview, Cancer Screening, Diagnosis, and Treatment, Preventing Cancer, Main Types of Cancer, Human Carcinogens.For all readers interested in the big picture view of cancer.
Cancer Biology
Author :Roger John Benjamin KingISBN :0131294547
Genre :Medical
File Size : 23.22 MB
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Providing an introduction of the biological principles of the causes and treatment of cancer, this book covers key topics in cancer biology. It is useful for students of cell biology, biochemistry, molecular biology, genetics and biomedical sciences, and postgraduate students moving into cancer research.
Introduction To Cancer Biology
Author :Robin HeskethISBN :9781107013988
Genre :Medical
File Size : 86.12 MB
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A concise overview of the fundamental concepts of cancer biology, ideal for those with little or no background in the field. From cancer epidemiology and the underlying mechanisms, through to tumour detection and treatment, the comprehensive picture revealed will enable students to move into the cancer field with confidence.
Cancer
Author :Gary S. SteinISBN :9781118962893
Genre :Science
File Size : 28.20 MB
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A guide to recent insights into the genetic and epigenetic parameters of cancer biology and pathology and emerging clinical applications The thoroughly updated second edition of The Biology and Treatment of Cancer, now titled Cancer: Prevention, Early Detection, Treatment and Recovery, goes beyond reviewing the fundamental properties of cancer biology and the relevant issues associated with treatment of the disease. The new edition contains coverage of additional 'patient centric' topics and presents cancer biology with selection of topics, facts, and perspectives written in easy-to-understand terms. With contributions from noted experts, the book explores recent advances in the understanding of cancer including breakthroughs in the molecular and cellular basis of cancer and provides strategies for approaching cancer prevention, early detection, and treatment. The authors incorporate recent information on the genetic and epigenetic parameters of cancer biology and pathology with indications of emerging clinical applications. The text offers a unique guide to cancer prevention, early detection, treatment, and recovery for students, caregivers, and most importantly cancer patients. This significant book: Incorporates current insight into the genetic and epigenetic parameters of cancer biology and pathology and information on emerging clinical applications Contains contributions from leaders in cancer research, care, and clinical trials Offers an accessible guide to an accurate and balanced understanding of cancer and the cancer patient Focuses on the importance of cancer prevention, early detection, treatment, and survivorship Written for medical students, students of cancer biology, and caregivers and cancer patients, Cancer: Prevention, Early Detection, Treatment and Recovery offers an authoritative overview of the challenges and opportunities associated with cancer biology, cancer research, and the spectrum of clinical considerations.
Cancer Biology
Author :R. J. B. KingISBN :0582404320
Genre :Medical
File Size : 56.37 MB
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Cancer Biology provides a clear, concise and authoritative introduction to the biological principles that underlie the causes and treatment of cancer, drawing on the author's extensive research and teaching experience to guide students through this complex subject. The study of cancer encompasses cell and molecular biology, biochemistry, epidemiology and medical sciences and this text brings together these diverse areas. The emphasis is on human aspects, with underlying principles illustrated by specific examples which are supplemented with data from other species where appropriate. The new edition has been updated throughout with new material on chemoprevention, DNA repair, telomerase, apoptosis, signal transduction, cell adhesion, angiogenesis and new treatments. A new appendix provides descriptions of 15 selected cancers, with data on cancer risks and survival rates, and notes on risk factors and metastasis. Features * Comprehensive up-to-date coverage of key topics in cancer biology * A human emphasis including principles of cancer treatment * Accessible single author text, with boxes, chapter summaries and clear two-colour diagrams * Updated coverage of diet and prevention, DNA repair, telomerase, apoptosis, signal transduction, cell adhesion, angiogenesis and new treatments * Extended and updated references, a new list of abbreviations and improved glossary * New appendix on features of 15 selected cancers, including breast cancer and leukaemia Cancer Biology is an essential text for students of cell biology, biochemistry, molecular biology, genetics and biomedical sciences. It will also be valuable to postgraduate students moving into cancerresearch. Roger King is Honorary Professor in Cellular Oncology at Surrey University, UK. He was formerly Chairman of the International Society for Hormones and Cancer, Head of the Hormone Biochemistry Department at the Imperial Cancer Research Fund Laboratories and a consultant to the World Health Organisation.
The Biology And Treatment Of Cancer
Author :Arthur B. PardeeISBN :9781118208458
Genre :Medical
File Size : 42.38 MB
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Cancer Biology
Author :Raymond W. RuddonISBN :9780195175431
Genre :Medical
File Size : 73.83 MB
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The fourth edition of this classic text provides a thorough, yet concise review of the cellular and molecular mechanisms involved in the transformation of normal into malignant cells, the invasiveness of cancer cells into host tissues, and the metastatic spread of cancer cells in the host organism. It defines the fundamental pathophysiologic changes that occur in tumor tissue and in the host animal or patient. Each chapter discusses the historical development of a field, citing the key experimental advances to the present day, and evaluates the current evidence that best supports or rules out concepts of the molecular and cellular mechanisms regulating cancer cell behavior. For all the areas of fundamental cancer research, an effort has been made to relate basic research findings to the clinical disease states. The book is well written and well illustrated, with schematic diagrams and actual research data to demonstrate points made in the text. There is also an extensive, up-to-date bibliography, making the book valuable to scientists, and to physicians, students, and nurses interested in the field of cancer biology. The topics covered include pathologic characterization of human tumors, epidemiology of human cancer, regulation of cell proliferation and differentiation, cellular and molecular phenotypic characteristics of the cancer cell, mechanisms of carcinogenesis, tumor initiation and promotion, viral carcinogenesis, oncogenes and oncogene products, growth factors, chromosomal alterations in cancer, mechanisms of tumor metastasis, host-tumor interactions, fundamental aspects of tumor immunology, and the advances in cancer cell biology that will lead to improved diagnosis and treatment of cancer in the future.
Therapeutic Strategies In Cancer Biology And Pathology
Author :Gajanan V. SherbetISBN :9780124165908
Genre :Medical
File Size : 62.82 MB
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Currently, intensive effort is being directed toward the identification of molecular targets that can provide approaches to the development of novel therapeutic strategies in cancer management. This book focuses on metastasis-associated genes, metastasis promoter and suppressor genes, which relate specifically to behavioral alterations of cancer cells in epithelial mesenchymal transition, cancer stem cell maintenance and propagation, and to the acquisition of invasive and metastasis faculty. The function of these genes has implications for cell cycle regulation and cell proliferation and so constitute an essential element in cancer growth and dissemination. The emphasis in this book is on how appropriate these genes are as molecular targets and how practicable are the constituents of their signal transduction systems as potential candidates and how accessible they are to targeted therapy. Written in a straightforward and clear style with background information supporting the new research, this book will be useful for students and researchers in cancer therapies. Identifies molecular targets and their accessibility for therapeutic intervention Provides information on biological features of tumor development and dissemination Background information provided for each topic
The Impact Of Tumor Biology On Cancer Treatment And Multidisciplinary Strategies
Author :Michael MollsISBN :9783540743866
Genre :Medical
File Size : 68.35 MB
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Te rapidly changing concepts in radiation oncology with the development of more precise - strumentation for delivery of radiation therapy and a greater emphasis on hypofractionation technologies require a very intimate knowledge of tumor biology and the infuence of various biologic factors on dose distribution within the tumor in terms of homogeneity as well as prev- tion of any late efects on normal tissue surrounding the tumor itself. Not only are these major factors in clinical practice but also the known factors of inhomogeneity of cancer cells, the impact of microenvironment in terms of radiation efect, and host factors make it mandatory to design therapeutic strategies to improve the outcome and to diminish any potential short-term or lo- term risks from the radiation therapy. Te authors have developed an outstanding text that deals with these strategies and how they would impact on established and emerging new technologies and treatment. Te context of the presentations within a multidisciplinary combined modality therapy program is incredibly - portant. In this volume, various topics are reviewed including tumor genesis, cell proliferation, - giogenesis, the physiologic characteristics of malignant tissues, invasion and adhesion, the route and role pursued in the development of metastasis, and the role of the human immune system in cancer prevention and development.
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Download Book Introduction To Cancer Biology in PDF format. You can Read Online Introduction To Cancer Biology here in PDF, EPUB, Mobi or Docx formats.Introduction To Cancer Biology
Author :ISBN :9788776814786
Genre :
File Size : 68.19 MB
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'Introduction to Cancer Biology is a short primer on how cancers develop and grow. The aim of this book is to provide a gentle exploration of the fundamental concepts in a easy-to-understand format, using examples and key figures for illustration. It is written in a style to help the reader understand the six basic principles that inform our current understanding of cancer, at the molecular, cellular and physiological level. The text can be used either as a first step towards a deeper understanding of the mechanisms of cancer progression or it can be used as a quick revision guide. It would be suitable for anyone, with or without a background in biology.'--Website.
Introduction To Cancer Biology
Author :Robin HeskethISBN :9781107013988
Genre :Medical
File Size : 82.85 MB
Format :PDF
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A concise overview of the fundamental concepts of cancer biology, ideal for those with little or no background in the field. From cancer epidemiology and the underlying mechanisms, through to tumour detection and treatment, the comprehensive picture revealed will enable students to move into the cancer field with confidence.
Introduction To The Cellular And Molecular Biology Of Cancer
Author :Margaret KnowlesISBN :0191513814
Genre :Medical
File Size : 39.2 MB
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. What is cancer?, L.M. Franks and Margaret A. Knowles. 2. The causes of cancer, Naomi Allen, Robert Newton, Amy Berrington de Gonzalez, Jane Green, Emily Banks, and Timothy J. Key. 3. Inherited Susceptibility to Cancer, D. Timothy Bishop. 4. DNA Repair and Cancer, Beate Koberle, John P. Wittschieben, and Richard D. Wood. 5. Epigenetic Events in Cancer, Jonathan C. Cheng and Peter A. Jones. 6. Molecular Cytogenetics of Cancer, Denise. Sheer and Janet Shipley. 7. Oncogenes, Margaret A. Knowles. 8. Tumour suppressor genes, Sonia Lain and David P. Lane. 9. The cancer cell cycle, Chris J. Norbury. 10. Cellular immortalization and telomerase activation in cancer, Robert F. Newbold. 11. Growth factors and their signalling pathways in cancer, Sally A. Prigent. 12. Apoptosis: molecular physiology and significance for cancer therapeutics, Dean A. Fennell. 13. Mechanisms of Viral Carcinogenesis, Paul Farrell. 14. Cytokines and Cancer, Peter W. Szlosarek and Frances R. Balkwill. 15. Hormones and cancer, Charlotte L. Bevan. 16. The spread of tumours, Ian Hart. 17. Angiogenesis, K.Tahtis and R.Bicknell. 18. Stem cells, heamopoiesis, and leukaemia, Mel Greaves. 19. Animal models of cancer, Jos Jonkers and Anton Berns. 20. The immunology of cancer, Peter C. L. Beverley. 21. The molecular pathology of cancer, Tatjana Crnogorac-Jurcevic, Richard Poulsom, and Nicholas R. Lemoine. 22. From transcriptome to proteome, Silvana Debernardi, Rachel Craven, Bryan D. Young, and Rosamonde E. Banks. 23. Local treatment of cancer, Ian S. Fentiman. 24. Chemotherapy, D.R. Camidge and D.I. Jodrell. 25. Radiotherapy and molecular radiotherapy, Anne Kiltie. 26. Monoclonal antibodies and therapy, T. Geldart, M.J. Glennie, and P.W.M. Johnson. 27. Immunotherapy of cancer, Andrew M. Jackson and Joanne Porte. 28. Cancer gene therapy, John David Chester. 29. Screening, Peter Sasieni and Jack Cuzick. 30. Conclusions and prospects, Peter Selby and Margaret A Knowles.
Cancer Biology
Author :Roger John Benjamin KingCancer Biology Pdf
ISBN :0131294547
Genre :Medical
File Size : 38.50 MB
Format :PDF, ePub
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Providing an introduction of the biological principles of the causes and treatment of cancer, this book covers key topics in cancer biology. It is useful for students of cell biology, biochemistry, molecular biology, genetics and biomedical sciences, and postgraduate students moving into cancer research.
Introduction To The Cellular And Molecular Biology Of Cancer
Author :Leonard Maurice FranksISBN :0198547323
Genre :Language Arts & Disciplines
File Size : 73.79 MB
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This new edition of Introduction to the Cellular and Molecular Biology of Cancer provides a concise yet comprehensive overview of cancer biology, covering the current status of both research and treatment. For the student or new researcher the breadth of cancer research can appear daunting, yet a broad understanding is essential for translation of laboratory findings into the clinic. Within the broad scope of the book, each topic is reviewed authoritatively by experts in the field, and the accompanying bibliographies allow rapid access to the relevant current literature. The book covers topics extending from the molecular alterations found in cancer cells and their causes to the current range of approaches to treatment. Since the publication of the previous edition in 1997 there has been unprecedented progress in cancer research: this is reflected by an extensive revision of all the material, and the addition of eight new chapters, covering DNA repair, epigenetic events, the cell cycle, cell immortalisation, apoptosis, angiogenesis, animal models, the genome, transcriptome and proteome, radiotherapy and molecular radiotherapy, immunotherapy, and gene therapy. The fourth edition of this popular book will serve as a text for both undergraduate and postgraduate use and also as an introduction for clinicians and scientists new to the field. Book jacket.
Cancer Biology
Author :R. J. B. KingISBN :0582404320
Genre :Medical
File Size : 40.4 MB
Format :PDF, ePub
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Cancer Biology provides a clear, concise and authoritative introduction to the biological principles that underlie the causes and treatment of cancer, drawing on the author's extensive research and teaching experience to guide students through this complex subject. The study of cancer encompasses cell and molecular biology, biochemistry, epidemiology and medical sciences and this text brings together these diverse areas. The emphasis is on human aspects, with underlying principles illustrated by specific examples which are supplemented with data from other species where appropriate. The new edition has been updated throughout with new material on chemoprevention, DNA repair, telomerase, apoptosis, signal transduction, cell adhesion, angiogenesis and new treatments. A new appendix provides descriptions of 15 selected cancers, with data on cancer risks and survival rates, and notes on risk factors and metastasis. Features * Comprehensive up-to-date coverage of key topics in cancer biology * A human emphasis including principles of cancer treatment * Accessible single author text, with boxes, chapter summaries and clear two-colour diagrams * Updated coverage of diet and prevention, DNA repair, telomerase, apoptosis, signal transduction, cell adhesion, angiogenesis and new treatments * Extended and updated references, a new list of abbreviations and improved glossary * New appendix on features of 15 selected cancers, including breast cancer and leukaemia Cancer Biology is an essential text for students of cell biology, biochemistry, molecular biology, genetics and biomedical sciences. It will also be valuable to postgraduate students moving into cancerresearch. Roger King is Honorary Professor in Cellular Oncology at Surrey University, UK. He was formerly Chairman of the International Society for Hormones and Cancer, Head of the Hormone Biochemistry Department at the Imperial Cancer Research Fund Laboratories and a consultant to the World Health Organisation.
Recent Reviews
Author :ISBN :MINN:31951D032446069
Genre :Cancer
File Size : 87.67 MB
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Computational Cancer Biology
Author :Mathukumalli VidyasagarISBN :9781447147510
Genre :Computers
File Size : 34.63 MB
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This brief introduces people with a basic background in probability theory to various problems in cancer biology that are amenable to analysis using methods of probability theory and statistics. The title mentions “cancer biology” and the specific illustrative applications reference cancer data but the methods themselves are more broadly applicable to all aspects of computational biology. Aside from providing a self-contained introduction to basic biology and to cancer, the brief describes four specific problems in cancer biology that are amenable to the application of probability-based methods. The application of these methods is illustrated by applying each of them to actual data from the biology literature. After reading the brief, engineers and mathematicians should be able to collaborate fruitfully with their biologist colleagues on a wide variety of problems.
Understanding Cancer
Author :J Richard McIntoshISBN :0367190125
Genre :
File Size : 74.66 MB
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Understanding Cancer is a brand-new, undergraduate textbook that uses simple language and well-chosen examples to explain the biological processes that underlie cancer and inform our diagnosis and treatment of the disease. Assuming no prior study of biology or chemistry, the book has been carefully designed to provide the relevant information for the many students who require an accessible introduction to the subject, including those undertaking a one-semester course while majoring in a discipline outside the biological sciences. Born of the author's personal experiences in life, the classroom, and in the laboratory as a professor of cell biology, the book presents stories of people touched by cancer, while maintaining a scientific perspective on what is known and still unknown about cancer's onset and development, its prognosis, and current methods of treatment. Key Features: A writing style that is simple and engaging but retains scientific precision Key concepts listed at the end of each chapter Beautiful, full-color presentation, extensive illustration and supplementary video material Plentiful use of sidebars to provide additional material on a broad range of subjects including cell architecture, protein function, DNA replication and repair, oncogenic viruses, and the adaptive immune system for students wishing to explore topics in greater depth and to encourage further study Describes the methods used in diagnosis - X-ray, tomography, MRI, and PET - and the approaches to treatment - surgery, chemotherapy, and activation of immune checkpoints - making clear the advances and limitations of medical technology Offers personal narratives of people affected by cancer, following them through the stages of their diagnosis and treatment to show the human faces of cancer Side questions in the margins throughout the book encourage students to think about what they are learning along the way, with answers provided at the end of the book while 'Thought questions' inspire a deeper level of analysis and concept synthesis, with answers provided only to instructors Concludes with a glossary of important terms, particularly helpful for those new to scientific study About the Author: J. Richard McIntosh is Distinguished Professor Emeritus in the Department of Molecular, Cellular, and Developmental Biology at the University of Colorado, Boulder. He taught freshman biology for 20 years, cancer biology for 9, and graduate cell biology for 45. His research has focused on mitosis, earning him an American Cancer Society Research Professorship and election to the National Academy of Sciences, USA.
Molecular Biology Of Cancer
Author :Lauren PecorinoISBN :9780199577170
Genre :Medical
File Size : 66.55 MB
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The third edition of The Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics offers a fresh approach to the study of the molecular basis of cancer, by showing how our understanding of the defective mechanisms which drive cancer is leading to the development of new targeted therapeutic agents.